Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation

Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation

Breast cancer stem cells (BCSCs) are tumor-initiating cells that possess the capacity for self-renewal. Cancer stem cells (CSCs) are responsible for poor outcomes caused by therapeutic resistance. In our study, we found that sulconazole—an antifungal medicine in the imidazole class&#82...

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Bibliographic Details
Main Authors: Hack Sun Choi, Ji-Hyang Kim, Su-Lim Kim, Dong-Sun Lee
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
sulconazole
NF-κB
IL-8
mammosphere
breast cancer stem cells
Online Access:https://www.mdpi.com/2073-4409/8/9/1007

Internet

https://www.mdpi.com/2073-4409/8/9/1007

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