Ether Lipid Deficiency in Mice Produces a Complex Behavioral Phenotype Mimicking Aspects of Human Psychiatric Disorders

Ether Lipid Deficiency in Mice Produces a Complex Behavioral Phenotype Mimicking Aspects of Human Psychiatric Disorders

Ether lipids form a specialized subgroup of phospholipids that requires peroxisomes to be synthesized. We have previously detected that deficiency in these lipids leads to a severe disturbance of neurotransmitter homeostasis and release as well as behavioral abnormalities, such as hyperactivity, in...

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Bibliographic Details
Main Authors: Fabian Dorninger, Anna Gundacker, Gerhard Zeitler, Daniela D. Pollak, Johannes Berger
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
plasmalogen
ether phospholipid
autism
behavior
peroxisome
social interaction
memory
neurotransmission
synapse
Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/20/16/3929

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https://www.mdpi.com/1422-0067/20/16/3929

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