The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring

Alterations in glucose and glutamine utilizing pathways and in fatty acid metabolism are currently considered the most significant and prevalent metabolic changes observed in almost all types of tumors. Glucose, glutamine and fatty acids are the substrates for the hexosamine biosynthetic pathway (HB...

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Bibliographic Details
Main Authors: Ferdinando Chiaradonna, Francesca Ricciardiello, Roberta Palorini
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/7/6/53