The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring
Alterations in glucose and glutamine utilizing pathways and in fatty acid metabolism are currently considered the most significant and prevalent metabolic changes observed in almost all types of tumors. Glucose, glutamine and fatty acids are the substrates for the hexosamine biosynthetic pathway (HB...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-06-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/7/6/53 |