Expression of Components of the Renin-Angiotensin System by the Putative Stem Cell Population Within WHO Grade I Meningioma

Expression of Components of the Renin-Angiotensin System by the Putative Stem Cell Population Within WHO Grade I Meningioma

Aim: We have recently demonstrated a putative stem cell population within WHO grade I meningioma (MG) that expressed embryonic stem cell (ESC) markers OCT4, NANOG, SOX2, KLF4 and c-MYC, localized to the endothelial and pericyte layers of the microvessels. There is increasing recognition that the ren...

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Bibliographic Details
Main Authors: Ganeshwaran Shivapathasundram, Agadha C. Wickremesekera, Helen D. Brasch, Bede van Schaijik, Reginald W. Marsh, Swee T. Tan, Tinte Itinteang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Surgery
Subjects:
meningioma
renin-angiotensin system
pro(renin) receptor
angiotensin converting enzyme
angiotensin II receptor I
angiotensin II receptor 2
Online Access:https://www.frontiersin.org/article/10.3389/fsurg.2019.00023/full

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https://www.frontiersin.org/article/10.3389/fsurg.2019.00023/full

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