RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

<p>Abstract</p> <p>Background</p> <p>With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident i...

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Bibliographic Details
Main Authors: Arcaro Alexandre, Eberhart Charles G, Stearns Duncan, Arnold Lucia, Oehler-Jänne Christoph, Shalaby Tarek, von Bueren André O, Pruschy Martin, Grotzer Michael A
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/10