Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids

Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids

Chondrosarcomas are malignant bone tumors. Their abundant cartilage-like extracellular matrix and their hypoxic microenvironment contribute to their resistance to chemotherapy and radiotherapy, and no effective therapy is currently available. MicroRNAs (miRNAs) may be an interesting alternative in t...

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Bibliographic Details
Main Authors: Clément Veys, Abderrahim Benmoussa, Romain Contentin, Amandine Duchemin, Emilie Brotin, Jérôme E. Lafont, Yannick Saintigny, Laurent Poulain, Christophe Denoyelle, Magali Demoor, Florence Legendre, Philippe Galéra
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
chondrosarcoma
miR-342-5p
miR-491-5p
Bcl-2/Bcl-xL
apoptosis
autophagy
Online Access:https://www.mdpi.com/1422-0067/22/11/5590

Internet

https://www.mdpi.com/1422-0067/22/11/5590

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