Real-World Methotrexate Dose on Clinical Effectiveness and Structural Damage of Certolizumab Pegol With Rheumatoid Arthritis

Objective: Rheumatoid arthritis (RA) treatments have markedly advanced with the introduction of biological agents, e. g., tumor necrosis factor (TNF) inhibitors. TNF inhibitors are demonstrated to be quite effective in combination with methotrexate (MTX), and sufficient doses of both agents are impo...

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Main Authors: Yuji Nozaki, Toshihiko Hidaka, Jinhai Ri, Tetsu Itami, Daisuke Tomita, Akinori Okada, Chisato Ashida, Fusayo Ikeda, Atsuhiro Yamamoto, Keiko Funahashi, Koji Kinoshita, Tsukasa Matsubara, Masanori Funauchi, Itaru Matsumura
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.643459/full