The role of endothelin-1 in the doxorubicin cardiotoxicity

Background: The cardiotoxicity of doxorubicin (Dx), an antineoplastic drug, is imposed by the development of cardiomyopathy and heart failure. The expression of endothelin-1 (ET-1) in myocardium under the action of Dx, directly correlates with the degree of cardiac dysfunction, mediated by endothe...

Full description

Bibliographic Details
Main Author: Lilia Tacu
Format: Article
Language:English
Published: Scientific Medical Association of Moldova 2020-10-01
Series:The Moldovan Medical Journal
Subjects:
Online Access:http://moldmedjournal.md/wp-content/uploads/2020/09/moldovan-med-j-2020-63-4-tacu-full-text.pdf