Respiratory syncytial virus induced type I IFN production by pDC is regulated by RSV-infected airway epithelial cells, RSV-exposed monocytes and virus specific antibodies.

Innate immune responses elicited upon virus exposure are crucial for the effective eradication of viruses, the onset of adaptive immune responses and for establishing proper immune memory. Respiratory syncytial virus (RSV) is responsible for a high disease burden in neonates and immune compromised i...

Full description

Bibliographic Details
Main Authors: Marcel A Schijf, Michael V Lukens, Debby Kruijsen, Nathalie O P van Uden, Johan Garssen, Frank E J Coenjaerts, Belinda Van't Land, Grada M van Bleek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24303065/pdf/?tool=EBI