Icariin Enhances Bone Repair in Rabbits with Bone Infection during Post-infection Treatment and Prevents Inhibition of Osteoblasts by Vancomycin

Icariin Enhances Bone Repair in Rabbits with Bone Infection during Post-infection Treatment and Prevents Inhibition of Osteoblasts by Vancomycin

Vancomycin is an effective antibiotic for treatment of bone infection caused by Staphylococcus aureus, however, a high local concentration of vancomycin might induce a delay in bone union. Icariin has been reported to suppress osteoclastogenes and promote osteogenesis. Our study aimed to investigate...

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Bibliographic Details
Main Authors: Yang Zhang, Lifeng Shen, Zhujun Mao, Nani Wang, Xuping Wang, Xiaowen Huang, Ying Hu, Dan Shou, Chengping Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Pharmacology
Subjects:
icariin
vancomycin
bone infection
post-infection treatment
bone repair
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00784/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00784/full

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