TNF -308G > A promoter polymorphism (rs1800629) and outcome from critical illness

Background: The susceptibility to adverse outcome from critical illness (occurrence of sepsis, septic shock, organ dysfunction/failure, and mortality) varies dramatically due to different degrees of inflammatory response. An over expression of tumor necrosis factor alpha (TNF-α) can lead to the prog...

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Bibliographic Details
Main Authors: Diego D’Ávila Paskulin, M.Sc., Paulo R.V. Fallavena, M.Sc., Francis J.O. Paludo, M.Sc., Thiago J. Borges, Juliane B. Picanço, Fernando S. Dias, Ph.D., Clarice Sampaio Alho, Ph.D.
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867011701817