How safe is TDF/FTC as PrEP? A systematic review and meta-analysis of the risk of adverse events in 13 randomised trials of PrEP

How safe is TDF/FTC as PrEP? A systematic review and meta-analysis of the risk of adverse events in 13 randomised trials of PrEP

Background: Tenofovir/emtricitabine (TDF/FTC) used as pre-exposure prophylaxis (PrEP) has proven benefits in preventing HIV infection. Widespread use of TDF/FTC can only be justified if the preventative benefits outweigh potential risks of adverse events. A previous meta-analysis of TDF/FTC compared...

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Bibliographic Details
Main Authors: Victoria Pilkington, Andrew Hill, Sophie Hughes, Nneka Nwokolo, Anton Pozniak
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Virus Eradication
Subjects:
Pre-exposure prophylaxis (PrEP), Safety, HIV, tenofovir, emtricitabine, kidney, bone density, adverse events
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020303125

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http://www.sciencedirect.com/science/article/pii/S2055664020303125

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