A reference haplotype panel for genome-wide imputation of short tandem repeats

A reference haplotype panel for genome-wide imputation of short tandem repeats

Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al. provide a SNP+STR haplotype reference panel that allows imputation of STRs from SNP array data.

Bibliographic Details
Main Authors: Shubham Saini, Ileena Mitra, Nima Mousavi, Stephanie Feupe Fotsing, Melissa Gymrek
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06694-0

Internet

https://doi.org/10.1038/s41467-018-06694-0

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