NSAID use and somatic exomic mutations in Barrett’s esophagus

NSAID use and somatic exomic mutations in Barrett’s esophagus

Abstract Background Use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been shown to protect against tetraploidy, aneuploidy, and chromosomal alterations in the metaplastic condition Barrett’s esophagus (BE) and to lower the incidence and mortality of esophageal adenocarcino...

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Bibliographic Details
Main Authors: Patricia C. Galipeau, Kenji M. Oman, Thomas G. Paulson, Carissa A. Sanchez, Qing Zhang, Jerry A. Marty, Jeffrey J. Delrow, Mary K. Kuhner, Thomas L. Vaughan, Brian J. Reid, Xiaohong Li
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Genome Medicine
Subjects:
Exome sequencing
Mutation
Apoptosis
Barrett’s esophagus
Esophageal adenocarcinoma
Aspirin
Online Access:http://link.springer.com/article/10.1186/s13073-018-0520-y

Internet

http://link.springer.com/article/10.1186/s13073-018-0520-y

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