Modeling Alzheimer’s disease with human iPS cells: advancements, lessons, and applications

One in three people will develop Alzheimer’s disease (AD) or another dementia and, despite intense research efforts, treatment options remain inadequate. Understanding the mechanisms of AD pathogenesis remains our principal hurdle to developing effective therapeutics to tackle this looming medical c...

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Bibliographic Details
Main Authors: Sofia Essayan-Perez, Bo Zhou, Amber M. Nabet, Marius Wernig, Yu-Wen Alvin Huang
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Neurobiology of Disease
Subjects:
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301573