Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel

Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel

Angiogenesis is critical to the growth of tumors. Vascularization-targeting agents, with or without cytotoxic drugs, are widely used for the treatment of several solid tumors including esophagogastric adenocarcinoma. However, little is known about the systemic effects of anti-angiogenic therapies an...

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Bibliographic Details
Main Authors: Anne Steins, Eva A. Ebbing, Marcel C. M. Pistorius, Cynthia Waasdorp, Kausilia K. Krishnadath, Jan Paul Medema, Johanna W. Wilmink, Ron A. A. Mathôt, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
angiogenesis
anti-angiogenic therapy
esophagogastric adenocarcinoma
nab-paclitaxel
pharmacokinetics
Online Access:http://dx.doi.org/10.1080/10717544.2017.1406559

Internet

http://dx.doi.org/10.1080/10717544.2017.1406559

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