Targeting peptide-decorated biomimetic lipoproteins improve deep penetration and cancer cells accessibility in solid tumor

The limited penetration of nanoparticles and their poor accessibility to cancer cell fractions in tumor remain essential challenges for effective anticancer therapy. Herein, we designed a targeting peptide-decorated biomimetic lipoprotein (termed as BL-RD) to enable their deep penetration and effici...

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Bibliographic Details
Main Authors: Tao Tan, Yuqi Wang, Jing Wang, Zhiwan Wang, Hong Wang, Haiqiang Cao, Jie Li, Yaping Li, Zhiwen Zhang, Siling Wang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519306276