Alternative Splicing of Differentiated Myeloid Cell Transcripts after Infection by Anaplasma phagocytophilum Impacts a Selective Group of Cellular Programs

Alternative Splicing of Differentiated Myeloid Cell Transcripts after Infection by Anaplasma phagocytophilum Impacts a Selective Group of Cellular Programs

Eukaryotic proteome diversity exceeds that encoded within individual genes, and results in part from alternative splicing events of pre-messenger RNA. The diversity of these splicing events can shape the outcome in development and differentiation of normal tissues, and is important in pathogenic cir...

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Bibliographic Details
Main Authors: J. Stephen Dumler, Sara H. Sinclair, Amol C. Shetty
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Anaplasma phagocytophilum
intracellular infection
RNA isoforms
RNAseq
spliceosome
gene ontology
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00014/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00014/full

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