Increased anxiety-like behavior following circuit-specific catecholamine denervation in mice

Increased anxiety-like behavior following circuit-specific catecholamine denervation in mice

Parkinson's disease (PD) presents with a constellation of non-motor symptoms, notably increased anxiety, which are currently poorly treated and underrepresented in animal models of the disease. Human post-mortem studies report loss of catecholaminergic neurons in the pre-symptomatic phases of P...

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Bibliographic Details
Main Authors: Sara Ferrazzo, Ozge Gunduz-Cinar, Nadia Stefanova, Gabrielle A. Pollack, Andrew Holmes, Claudia Schmuckermair, Francesco Ferraguti
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Neurobiology of Disease
Subjects:
Anxiety
Fear learning
Amygdala
Parkinson's disease
Dopamine
Noradrenaline
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119300142

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http://www.sciencedirect.com/science/article/pii/S0969996119300142

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