Unraveling the Early Events of Amyloid-β Protein (Aβ) Aggregation: Techniques for the Determination of Aβ Aggregate Size

Unraveling the Early Events of Amyloid-β Protein (Aβ) Aggregation: Techniques for the Determination of Aβ Aggregate Size

The aggregation of proteins into insoluble amyloid fibrils coincides with the onset of numerous diseases. An array of techniques is available to study the different stages of the amyloid aggregation process. Recently, emphasis has been placed upon the analysis of oligomeric amyloid species, which ha...

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Bibliographic Details
Main Authors: N. Elizabeth Pryor, Melissa A. Moss, Christa N. Hestekin
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid
capillary electrophoresis
centrifugation
fluorescence correlation spectroscopy
light scattering
mass spectrometry
polyacrylamide gel electrophoresis
oligomer
size exclusion chromatography
Western blotting
Online Access:http://www.mdpi.com/1422-0067/13/3/3038/

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http://www.mdpi.com/1422-0067/13/3/3038/

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