Nucleic acids in inclusion bodies obtained from E. coli cells expressing human interferon-gamma
Abstract Background Inclusion bodies (IBs) are protein aggregates in recombinant bacterial cells containing mainly the target recombinant protein. Although it has been shown that IBs contain functional proteins along with protein aggregates, their direct application as pharmaceuticals is hindered by...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-020-01400-6 |