Nucleic acids in inclusion bodies obtained from E. coli cells expressing human interferon-gamma

Abstract Background Inclusion bodies (IBs) are protein aggregates in recombinant bacterial cells containing mainly the target recombinant protein. Although it has been shown that IBs contain functional proteins along with protein aggregates, their direct application as pharmaceuticals is hindered by...

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Bibliographic Details
Main Authors: Elena Krachmarova, Ivan Ivanov, Genoveva Nacheva
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-020-01400-6