Human CD8+ CD57- TEMRA cells: Too young to be called "old".

End-stage differentiation of antigen-specific T-cells may precede loss of immune responses against e.g. viral infections after allogeneic stem cell transplantation (SCT). Antigen-specific CD8+ T-cells detected by HLA/peptide multimers largely comprise CD45RA-/CCR7- effector memory (TEM) and CD45RA+/...

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Bibliographic Details
Main Authors: Kriti Verma, Justyna Ogonek, Pavankumar Reddy Varanasi, Susanne Luther, Ivonne Bünting, Katrin Thomay, Yvonne Lisa Behrens, Eva Mischak-Weissinger, Lothar Hambach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5421808?pdf=render