Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?

Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?

Sarcolipin (SLN) is a regulator of sarco/endo plasmic reticulum Ca2+-ATPase (SERCA) pump and has been shown to be involved in muscle nonshivering thermogenesis (NST) and energy metabolism. Interestingly, SLN expression is significantly upregulated both during muscle development and in several diseas...

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Bibliographic Details
Main Authors: Naresh C. Bal, Subash C. Gupta, Meghna Pant, Danesh H. Sopariwala, Geoffrey Gonzalez-Escobedo, Joanne Turner, John S. Gunn, Christopher R. Pierson, Scott Q. Harper, Jill A. Rafael-Fortney, Muthu Periasamy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
sarcolipin
skeletal muscle
muscle disease
sarco/endo plasmic reticulum Ca2+ ATPase
Ca2+-handling proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.633058/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.633058/full

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