Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats

Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats

Hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitors were developed for treatment of renal anemia. Patients applicable for HIF-PHD inhibitor treatment experience complications such as chronic kidney disease, whereby water and electrolyte homeostasis is disrupted. The effects of hypoxia-i...

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Bibliographic Details
Main Authors: Anqi Zhang, Daisuke Nakano, Norihiko Morisawa, Kento Kitada, Wararat Kittikulsuth, Asadur Rahman, Takashi Morikawa, Yoshio Konishi, Akira Nishiyama
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Pharmacological Sciences
Subjects:
Salt
Prolyl hydroxylase
Blood pressure
Online Access:http://www.sciencedirect.com/science/article/pii/S134786132100027X

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http://www.sciencedirect.com/science/article/pii/S134786132100027X

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