Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages
Macrophage-derived lipases are associated with atherosclerosis in human and animal studies. Despite numerous non-lipid-lowering effects of statins, their effect on macrophage LPL and endothelial lipase (EL) expression has not been investigated. In the present study, atorvastatin and simvastatin dose...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007-10-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520424563 |