It is time for top-down venomics
Abstract The protein composition of animal venoms is usually determined by peptide-centric proteomics approaches (bottom-up proteomics). However, this technique cannot, in most cases, distinguish among toxin proteoforms, herein called toxiforms, because of the protein inference problem. Top-down pro...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SciELO
2017-10-01
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Series: | Journal of Venomous Animals and Toxins including Tropical Diseases |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40409-017-0135-6 |