Patterns of occurrence and implications of neratinib-associated diarrhea in patients with HER2-positive breast cancer: analyses from the randomized phase III ExteNET trial

Patterns of occurrence and implications of neratinib-associated diarrhea in patients with HER2-positive breast cancer: analyses from the randomized phase III ExteNET trial

Abstract Background We characterized patterns of occurrence and the impact of neratinib-associated diarrhea in the absence of protocol-directed antidiarrheal prophylaxis or a formal diarrhea management plan using data from Extended Adjuvant Treatment of Breast Cancer with Neratinib (ExteNET). Method...

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Bibliographic Details
Main Authors: Joanne Mortimer, Jack Di Palma, Kendra Schmid, Yining Ye, Mohammad Jahanzeb
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Breast Cancer Research
Subjects:
Early-stage breast cancer
HER2 positive
Neratinib
Pan-HER inhibition
Diarrhea
Health-related quality of life
Online Access:http://link.springer.com/article/10.1186/s13058-019-1112-5

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http://link.springer.com/article/10.1186/s13058-019-1112-5

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