Trans-omic Analysis Reveals ROS-Dependent Pentose Phosphate Pathway Activation after High-Frequency Electrical Stimulation in C2C12 Myotubes

Trans-omic Analysis Reveals ROS-Dependent Pentose Phosphate Pathway Activation after High-Frequency Electrical Stimulation in C2C12 Myotubes

Summary: Skeletal muscle adaptation is mediated by cooperative regulation of metabolism, signal transduction, and gene expression. However, the global regulatory mechanism remains unclear. To address this issue, we performed electrical pulse stimulation (EPS) in differentiated C2C12 myotubes at low...

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Bibliographic Details
Main Authors: Daisuke Hoshino, Kentaro Kawata, Katsuyuki Kunida, Atsushi Hatano, Katsuyuki Yugi, Takumi Wada, Masashi Fujii, Takanori Sano, Yuki Ito, Yasuro Furuichi, Yasuko Manabe, Yutaka Suzuki, Nobuharu L. Fujii, Tomoyoshi Soga, Shinya Kuroda
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Biochemistry
Physiology
Human Metabolism
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307501

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http://www.sciencedirect.com/science/article/pii/S2589004220307501

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