Mapping Solute Clearance From the Mouse Hippocampus Using a 3D Imaging Cryomicrotome

The hippocampus is susceptible to protein aggregation in neurodegenerative diseases such as Alzheimer’s disease. This protein accumulation is partially attributed to an impaired clearance; however, the removal pathways for fluids and waste products are not fully understood. The aim of this study was...

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Bibliographic Details
Main Authors: Daphne M. P. Naessens, Johannes G. G. Dobbe, Judith de Vos, Ed VanBavel, Erik N. T. P. Bakker
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.631325/full