Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases

Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases

The c-Jun N-terminal kinase (JNK) is highly evolutionarily conserved and plays important roles in a broad range of physiological and pathological processes. The WD40-repeat protein 62 (WDR62) is a scaffold protein that recruits different components of the JNK signaling pathway to regulate several hu...

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Bibliographic Details
Main Authors: Yiqiang Zhi, Xiaokun Zhou, Jurui Yu, Ling Yuan, Hongsheng Zhang, Dominic C. H. Ng, Zhiheng Xu, Dan Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
WDR62
JNK signaling
neurological disorders
reproductive diseases
tumorigenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.640753/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.640753/full

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