The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts

The heterogeneous properties of dermal cell populations have been posited to contribute toward fibrotic, imperfect wound healing in mammals. Here we characterize an adult population of dermal fibroblasts that maintain an active Prrx1 enhancer which originally marked mesenchymal limb progenitors. In...

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Bibliographic Details
Main Authors: Joshua D. Currie, Lidia Grosser, Prayag Murawala, Maritta Schuez, Martin Michel, Elly M. Tanaka, Tatiana Sandoval-Guzmán
Format: Article
Language:English
Published: The Company of Biologists 2019-07-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/7/bio043711