Shifting Valproic Acid to Levetiracetam in Women of Childbearing Age With Epilepsy: A Retrospective Investigation and Review of the Literature

Shifting Valproic Acid to Levetiracetam in Women of Childbearing Age With Epilepsy: A Retrospective Investigation and Review of the Literature

Objective: Valproic acid is the most high-risk teratogenic antiepileptic drug, and it may lead to fetal major congenital malformations. However, it is still used in women of childbearing age with epilepsy. The aim of this study was to report our experience of discontinuing or lowering valproic acid...

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Bibliographic Details
Main Authors: Cheng-Yen Kuo, Yi-Hsuan Liu, I-Jun Chou, Huei-Shyong Wang, Po-Cheng Hung, Min-Liang Chou, Jainn-Jim Lin, Shih-Yun Lan, Meng-Ying Hsieh, Yi-Shan Wang, Kuang-Lin Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neurology
Subjects:
women with epilepsy
major congenital malformation
valproic acid
levetiracetam
switching
pregnancy
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00330/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00330/full

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