A New Modified Histogram Matching Normalization for Time Series Microarray Analysis

Microarray data is often utilized in inferring regulatory networks. Quantile normalization (QN) is a popular method to reduce array-to-array variation. We show that in the context of time series measurements QN may not be the best choice for this task, especially not if the inference is based on con...

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Bibliographic Details
Main Authors: Laura Astola, Jaap Molenaar
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Microarrays
Subjects:
Online Access:http://www.mdpi.com/2076-3905/3/3/203