Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration

Abstract Endogenous β cell regeneration could alleviate diabetes, but proliferative stimuli within the islet microenvironment are incompletely understood. We previously found that β cell recovery following hypervascularization-induced β cell loss involves interactions with endothelial cells (ECs) an...

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Bibliographic Details
Main Authors: Diane C. Saunders, Kristie I. Aamodt, Tiffany M. Richardson, Alexander J. Hopkirk, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, David K. Flaherty, Nripesh Prasad, Shawn E. Levy, Alvin C. Powers, Marcela Brissova
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00129-z

Internet

https://doi.org/10.1038/s41536-021-00129-z

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