Porcine somatic cell nuclear transfer using telomerase reverse transcriptase-transfected mesenchymal stem cells reduces apoptosis induced by replicative senescence
Mesenchymal stem cells (MSCs) have been widely used as donor cells for somatic cell nuclear transfer (SCNT) to increase the efficiency of embryo cloning. Since replicative senescence reduces the efficiency of embryo cloning in MSCs during in vitro expansion, transfection of telomerase reverse transc...
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Format: | Article |
Language: | English |
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The Korean Society of Animal Reproduction and Biotechnology
2020-09-01
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Series: | Journal of Animal Reproduction and Biotechnology |
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Online Access: | http://www.e-jarb.org/journal/view.html?uid=2540&vmd=Full |