Porcine somatic cell nuclear transfer using telomerase reverse transcriptase-transfected mesenchymal stem cells reduces apoptosis induced by replicative senescence

Mesenchymal stem cells (MSCs) have been widely used as donor cells for somatic cell nuclear transfer (SCNT) to increase the efficiency of embryo cloning. Since replicative senescence reduces the efficiency of embryo cloning in MSCs during in vitro expansion, transfection of telomerase reverse transc...

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Bibliographic Details
Main Author: Ryounghoon Jeon
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2020-09-01
Series:Journal of Animal Reproduction and Biotechnology
Subjects:
Online Access:http://www.e-jarb.org/journal/view.html?uid=2540&vmd=Full