Intramuscular Clodronate in Long-Term Treatment of Symptomatic Knee Osteoarthritis: A Randomized Controlled Study

Abstract Background and Objective Clodronate is a nitrogen-free bisphosphonate that is widely and effectively used in the treatment of many osteo-metabolic disorders. The objective of our study was to evaluate the effectiveness of clodronate in reducing pain and bone marrow edema in knee osteoarthri...

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Bibliographic Details
Main Authors: Bruno Frediani, Carmela Toscano, Paolo Falsetti, Antonella Nicosia, Serena Pierguidi, Alberto Migliore, Stefano Giannotti, Luca Cantarini, Edoardo Conticini
Format: Article
Language:English
Published: Adis, Springer Healthcare 2020-02-01
Series:Drugs in R&D
Online Access:https://doi.org/10.1007/s40268-020-00294-4