Dying to Be Noticed: Epigenetic Regulation of Immunogenic Cell Death for Cancer Immunotherapy

Dying to Be Noticed: Epigenetic Regulation of Immunogenic Cell Death for Cancer Immunotherapy

Immunogenic cell death (ICD) activates both innate and adaptive arms of the immune system during apoptotic cancer cell death. With respect to cancer immunotherapy, the process of ICD elicits enhanced adjuvanticity and antigenicity from dying cancer cells and consequently, promotes the development of...

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Bibliographic Details
Main Authors: Brianne Cruickshank, Michael Giacomantonio, Paola Marcato, Sherri McFarland, Jonathan Pol, Shashi Gujar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
immunogenic cell death
epigenetics
T cell immunity
cancer immunotherapy
immune evasion
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00654/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00654/full

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