Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinases

Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinases

Bile acids (BAs) have been implicated in the development of oesophagitis, Barrett’s oesophagus and oesophageal adenocarcinoma (OAC). However, whether BAs promote cancer invasiveness has not been elucidated. We evaluated the role of BAs, in particular deoxycholic acid (DCA), in OAC invasion. Migratio...

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Bibliographic Details
Main Authors: Fran Quilty, Anne-Marie Byrne, John Aird, Sheeren El Mashad, Adolfo Parra-Blanco, Aideen Long, John F Gilmer, Carlos Medina
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
deoxycholic acid
matrix metalloproteinases
mmp-10
oesophageal adenocarcinoma
Online Access:https://www.mdpi.com/1422-0067/21/21/8042

Internet

https://www.mdpi.com/1422-0067/21/21/8042

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