Cutoff Finder: a comprehensive and straightforward Web application enabling rapid biomarker cutoff optimization.

Gene or protein expression data are usually represented by metric or at least ordinal variables. In order to translate a continuous variable into a clinical decision, it is necessary to determine a cutoff point and to stratify patients into two groups each requiring a different kind of treatment. Cu...

Full description

Bibliographic Details
Main Authors: Jan Budczies, Frederick Klauschen, Bruno V Sinn, Balázs Győrffy, Wolfgang D Schmitt, Silvia Darb-Esfahani, Carsten Denkert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522617?pdf=render