Functional Expression and Regulation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels (HCN) in Mouse iPS Cell-derived Cardiomyocytes after UTF1-Neo Selection

Functional Expression and Regulation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels (HCN) in Mouse iPS Cell-derived Cardiomyocytes after UTF1-Neo Selection

Background/Aims: In vitro reprogramming of somatic cells holds great potential to serve as an autologous source of cells for tissue repair. However, major difficulties in achieving this potential include obtaining homogeneous and stable cells for transplantation. High electrical activity of cells su...

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Bibliographic Details
Main Authors: Judith Semmler, Martin Lehmann, Kurt Pfannkuche, Michael Reppel, Jürgen Hescheler, Filomain Nguemo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cardiomyocytes
Heart development
Induced pluripotent stem cells
Hyperpolarization-activated cation channel
Whole-cell patch-clamp
Online Access:http://www.karger.com/Article/FullText/366332

Internet

http://www.karger.com/Article/FullText/366332

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