Increased β-Carboline 9N-Methyltransferase Activity in the Frontal Cortex in Parkinson's Disease
Enzymatic β-carboline N-methyltransferase activities generate N-methylated β-carbolinium cations that are analogs of the parkinsonian-producing neurotoxin MPP+. We measured β-carboline-2N-methyltransferase and β-carboline-9N-methyltransferase activities in the supernatant and particulate fractions f...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2000-06-01
|
| Series: | Neurobiology of Disease |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996100902870 |