Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus

In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis. In a previous paper, we showed that the methylation of H3K4 and consequent promoter nucleosome deacetylation repress ste11 induction and cell differentiation (Materne et al.,...

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Bibliographic Details
Main Authors: Philippe Materne, Enrique Vázquez, Mar Sánchez, Carlo Yague-Sanz, Jayamani Anandhakumar, Valerie Migeot, Francisco Antequera, Damien Hermand
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/13500