Synthesis and RP-TLC lipophilicity evaluation of a novel fluocinolon acetonide soft drug derivative
Cortienic acid was obtained by periodic acid oxidation of fluocinolone acetonide, whereas corresponding amide was synthesized from the cortienic acid and ethyl ester of b-alanine by dicyclohexylcarbodiimide - hydroxybenzotriazole coupling procedure. Lipophilicity of the amide was evaluated by using...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
University of Kragujevac, Faculty of Science
2016-01-01
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Series: | Kragujevac Journal of Science |
Subjects: | |
Online Access: | http://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2016/1450-96361638107D.pdf |