Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant

Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant

Background: There are differences in pharmacokinetic of mycophenolic acid among individuals. The UGT1A9 enzyme is of special interest since it is the main enzyme involved in the glucuronidation of MPA. Single nucleotide polymorphisms in the UGT1A9 gene may be responsible for individual differences i...

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Bibliographic Details
Main Authors: H. S. Ciftci, E. Demir, M. S. Karadeniz, T. Tefik, I. Nane, F. S. Oguz, F. Aydin, A. Turkmen
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Renal Failure
Subjects:
Pharmacokinetic
renal transplantation
rejection
blood concentrations
UGT polymorphism
Online Access:http://dx.doi.org/10.1080/0886022X.2018.1489285

Internet

http://dx.doi.org/10.1080/0886022X.2018.1489285

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