Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions

Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions

Summary: The human intestinal mucosa is a critical site for absorption, distribution, metabolism, and excretion (ADME)/Tox studies in drug development and is difficult to recapitulate in vitro. Using bioprinting, we generated three-dimensional (3D) intestinal tissue composed of human primary intesti...

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Bibliographic Details
Main Authors: Lauran R. Madden, Theresa V. Nguyen, Salvador Garcia-Mojica, Vishal Shah, Alex V. Le, Andrea Peier, Richard Visconti, Eric M. Parker, Sharon C. Presnell, Deborah G. Nguyen, Kelsey N. Retting
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300245

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http://www.sciencedirect.com/science/article/pii/S2589004218300245

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