Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease

Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease

Guillot-Sestier et al investigated sex-related differences in microglia in postmortem brain tissue from Alzheimer’s Disease (AD) patients as well as in the APP/PS1 AD mouse model. They demonstrated that there was differential expression of genes associated with microglial activation and metabolism b...

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Bibliographic Details
Main Authors: Marie-Victoire Guillot-Sestier, Ana Rubio Araiz, Virginia Mela, Aline Sayd Gaban, Eoin O’Neill, Lisha Joshi, Edward T. Chouchani, Evanna L. Mills, Marina A. Lynch
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02259-y

Internet

https://doi.org/10.1038/s42003-021-02259-y

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