Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease
Guillot-Sestier et al investigated sex-related differences in microglia in postmortem brain tissue from Alzheimer’s Disease (AD) patients as well as in the APP/PS1 AD mouse model. They demonstrated that there was differential expression of genes associated with microglial activation and metabolism b...
Main Authors: | Marie-Victoire Guillot-Sestier, Ana Rubio Araiz, Virginia Mela, Aline Sayd Gaban, Eoin O’Neill, Lisha Joshi, Edward T. Chouchani, Evanna L. Mills, Marina A. Lynch |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02259-y |
Similar Items
-
Brain injury, neuroinflammation and Alzheimer’s disease
by: Joshua eBreunig, et al.
Published: (2013-07-01) -
Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.
by: Takashi Mori, et al.
Published: (2013-01-01) -
Pivotal temperature and sexual dimorphism of Podocnemis expansa hatchlings (Testudines: Podocnemididae) from Bananal Island, Brazil
by: Adélio Lubiana, et al.
Published: (2009-09-01) -
Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet
by: Maude Bordeleau, et al.
Published: (2020-09-01) -
Names and Social Contracts: Late Gaelic Ireland and Celtic Studies
by: Eoin O’Neill