An NMR metabolomic study on the effect of alendronate in ovariectomized mice.

Alendronate sodium (Fosamax) is most widely used for the prevention and treatment of osteoporosis. It is a type of anti-resorptive agent that reduces the risk of fractures by changing bone turnover and bone mineral density. We investigated the effect of Fosamax on a mouse model of osteoporosis. Twen...

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Bibliographic Details
Main Authors: Shin-Yu Chen, Hui-Tzu Yu, Ju-Po Kao, Chung-Chun Yang, Shen-Shih Chiang, Darya O Mishchuk, Jeng-Leun Mau, Carolyn M Slupsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153652?pdf=render