A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.

A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.

Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence within the endemic regions of the Pampas in Argenti...

Full description

Bibliographic Details
Main Authors: Steven J Hallam, John T Manning, Junki Maruyama, Alexey Seregin, Cheng Huang, David H Walker, Juan Carlos de la Torre, Slobodan Paessler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008555

Internet

https://doi.org/10.1371/journal.pntd.0008555

Similar Items