Effects of Spider Venom Toxin PWTX-I (6-Hydroxytrypargine) on the Central Nervous System of Rats

Effects of Spider Venom Toxin PWTX-I (6-Hydroxytrypargine) on the Central Nervous System of Rats

The 6-hydroxytrypargine (6-HT) is an alkaloidal toxin of the group of tetrahydro-b-carbolines (THbC) isolated from the venom of the colonial spider Parawixia bistriata. These alkaloids are reversible inhibitors of the monoamine-oxidase enzyme (MAO), with hallucinogenic, tremorigenic and anxiolytic p...

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Bibliographic Details
Main Authors: Mario S. Palma, Jackson C. Bittencourt, Andrea A. Tavares, Carol F. Elias, Jaderson C. Da Costa, Lilian M. M. Cesar-Tognoli, Simone D. Salamoni
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Toxins
Subjects:
6-hydroxytrypargine
fos protein
immunohistochemistry
hypothalamus
hippocampus
epilepsy
NMDA
neurotoxicity
Online Access:http://www.mdpi.com/2072-6651/3/2/142/

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http://www.mdpi.com/2072-6651/3/2/142/

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